Posted: Mon December 25 4:18 PM EST  
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The Advantages of THCV Science

 

Claims that THC is one of the most well-known cannabinoids, but are you familiar with THCV? Although THCV is not as well-known as other cannabinoids, cannabis aficionados may still benefit greatly from it. One noteworthy advantage of THC is that it suppresses hunger, which draws users who want to experience its intoxicating effects while trying to shed or maintain a certain weight. Learn about the effects of THCV supported by research by continuing to read.

To begin with, what is THCV? 

Tetrahydrocannabivarin, or THCV for short, is a class II minor cannabinoid. This indicates that it is present in less amounts than THC and CBD, the two main cannabinoids. THCV is present in cannabis and hemp plants, where it may be taken as an isolated extract, usually in the form of oil, or ingested in plant material.

THCV lacks the intoxicating effects of THC when taken in low to moderate dosages. Higher dosages of THCV do, however, have unique psychedelic properties that are often regarded as euphoric and clear-headed.

How is THCV different from THC?

Chemically, the main distinction between THC and THCV is that THC has a 5-carbon molecular group, while THCV has a 3-carbon molecular group. The two cannabinoids vary significantly in how they affect cannabis users due to this little chemical variation.

As previously stated, THCV's primary benefit over THC is its absence of psychotropic effects. Another notable distinction between the two is that THCV inhibits appetite whilst THC increases hunger or the "munchies."

What advantages does THCV offer?

THCV has many advantages and reduces the signs and symptoms of several illnesses. Although its main effect is appetite suppression, there are other health advantages for users. Check out these scientifically proven medicinal advantages of THCV.

THCV May Reduce Hunger and Promote Weight Loss

The capacity of  THCv Isolate to decrease hunger may be its best-known advantage, since it may aid in weight loss. THCV inhibits the receptor that causes the hunger hormone, as opposed to THC, which causes the "munchies."

Reducing appetite on its own may aid in weight reduction, but cutting carbohydrates isn't the only thing happening. According to a 2013 study on THCV that was posted on the National Centre for Biotechnology Information, THCV may raise energy expenditure, which translates into increased calorie burning.

Furthermore, the Journal of Cannabis Research released a review of previous THCV research in 2020 and said that THCV suppresses hunger and regulates blood sugar levels. The evaluated literature examined diabetes and obesity in both people and mice.

THCV Could Control Blood Sugar Levels

THCV may be beneficial for those with Type II diabetes! A 2013 study that was published in the U.S. National Library of Medicine's National Centre for Biotechnology Information indicates that THCV has potential as a blood sugar regulator and insulin resistance reducer.

In a Harvard Medical School research, participants who said they had used marijuana during the previous month had smaller waist circumferences, higher levels of HDL-C (high-density lipoprotein, or "good"), lower levels of fasting insulin, and HOMA-IR (insulin resistance).

Who knows, maybe THCV may help you regain your beach-ready figure!

THCV could lessen seizure frequency.

According to a 2015 analysis that appeared in the Journal of Clinical Pharmacy and Therapeutics,  THCv Isolate may be able to lessen the frequency of seizures in people with epilepsy. Evidence shows that THCV, both taken prophylactically and when given during the event, may decrease the frequency and severity of seizures.

In an effort to produce a non-euphoric medication that may be used to treat epilepsy in both adults and children, current research is being done to synthesise cannabis derivatives and marijuana strains with low THC and medium THCV contents.

Application of THCV to Promote Neuroprotection and Muscle Control

It's crucial to understand that THCV may bind to the body's endocannabinoid system's CB1 and CB2 receptors in order to explain this advantage. The vast network of receptors, diverse ligands, and enzymes that catalyse the production and degradation of ligands make up the endogenous cannabinoid system, also known as the endocannabinoid system.

According to that theory, THCV has neuroprotective qualities and may be helpful in treating Parkinson's disease, according to a 2020 research conducted on mice and published in the journal Neurobiology of Disease. The British Journal of Pharmacology reported in a 2020 study that THCV had promise in the management of neuroinflammation and Huntington's disease.

THCV may lessen Alzheimer's disease symptoms.

Very modest dosages of tetrahydrocannabinol (THC) have been shown to decrease the synthesis of beta-amyloid proteins, which are regarded to be a signature feature and a major factor in the course of Alzheimer's disease, according to a preclinical research published in the Journal of Alzheimer's Disease.

As THCV replicates the effects of THC, it may be able to reduce the synthesis of beta-amyloid proteins, which are believed to be a defining feature and a major factor in the development of Alzheimer's disease.

THCV may promote the development of bones.

Evidence shows that  THCv Isolate plays key functions in bone metabolism by regulating bone mass, bone loss, and bone cell activity via its action on cannabinoid receptors within the skeletal endocannabinoid system.

The potential of this cannabinoid to cure osteoporosis and other degenerative bone-related illnesses is being investigated more and more as scientists gain insight into this process and the manner in which THCV connects to the receptors that control bone mass.

THCV may lessen panic episodes and anxiety.

While there is disagreement about whether cannabis usage may really lessen mental symptoms, several research support this idea. A 2019 study suggests that cannabis may lessen the symptoms of post-traumatic stress disorder (PTSD). Moreover, THCV could lessen panic episodes.

THCV as a medication: an anti-inflammatory and analgesic

THCV has been the subject of several scientific research that demonstrate its potential advantages, despite its lower popularity compared to other cannabinoids.

According to a 2010 THCV research that was written up in the British Journal of Pharmacology, it may lessen the inflammatory pain and inflammation-related symptoms in rats. Following inflammatory exposure, the mice in that research were given THCV once a day for four days straight. Not only did the molecule show promise in reducing inflammation, but the researchers also found that the mice did not acquire a tolerance to it.

According to 2013 study released by the National Centre for Biotechnology Information, U.S. National Library of Medicine, THCV is regarded as a minimal cannabinoid. It came to the conclusion that, in many cases, cannabinoids could be a helpful addition to the analgesic medications now on the market, particularly at low dosages that don't cause hyperalgesia—an increase in the sensitivity to pain—or other negative effects.

THCV Advantages: Concluding Remarks

Unlike THC and CBD, THCV is regarded as a minor cannabinoid, yet it nevertheless has therapeutic advantages for cannabis users. Science-backed THCV has the potential to treat a number of illnesses, including diabetes, obesity, anxiety, and Alzheimer's disease. Because of its analgesic and anti-inflammatory qualities, THCV may potentially be used as a medication.

Even though low to moderate amounts of THCV may not cause users to feel "high," when taken in substantially higher concentrations, they may nonetheless imitate the psychoactive effects. To get the most out of THCV and get all of its advantages, moderation is key.


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